eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
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Webinar: NIH Grants Process: Walk-Through for Beginners
May 5, 2024 7:47 PM
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Recent Publications
Mosley JD, Shelley JP, Dickson AL, Zanussi J, Kawai VK, et al. Clinical associations with a polygenic predisposition to benign lower white blood cell counts. Nature communications. 2024 Apr 22;15(1):3384.
Vessels T, Strayer N, Lee H, Choi KW, Ruderfer DM. Integrating Electronic Health Records and Polygenic Risk to Identify Genetically Unrelated Comorbidities of Schizophrenia That May Be Modifiable. Biological psychiatry global open science. 2024 May;4(3):100297.
Hui D, Dudek S, Kiryluk K, Walunas TL, Ritchie MD, et al. Risk factors affecting polygenic score performance across diverse cohorts. medRxiv : the preprint server for health sciences. 2024 Apr 10;.
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